Proline Promass U 500 Coriolis flowmeter

Maxima Automation Promass U 500 enables accurate, single-use Coriolis flow measurement for biopharma with cGMP compliance and automated verification

Field of Application :

The Promass U 500 is a single-use flowmeter designed specifically for biopharmaceutical applications in the life sciences industry. It supports the transition from batch to continuous manufacturing and multi-use to single-use devices, ensuring high accuracy and compliance with cGMP standards. It is particularly suited for upstream and downstream processes in monoclonal antibodies (mAb) production.

Key Applications :

Single-use flow measurement in biopharmaceutical production
Upstream and downstream processing in monoclonal antibody (mAb) manufacturing
Continuous manufacturing and process monitoring in life sciences

Device Properties :

Coriolis flow measurement with multivariable capability
Disposable sensor component, available in four line sizes
Permanently installed base unit, compatible with all sensor sizes
Automatic flow range detection with Heartbeat Technology
Factory-calibrated and verified after installation – no field calibration needed
Built-in web server, WLAN connectivity, and up to 4 I/Os for easy operation and process monitoring

Key Benefits :

Unmatched Accuracy & Compliance

Best-in-class accuracy – Coriolis technology ensures precise multivariable measurement
cGMP-compliant design – meets the latest industry standards and regulatory requirements

Flexibility & Ease of Use

High flexibility – one sensor fits all disposable line sizes
Fast and simple commissioning – one-hand mounting and automated calibration data transfer

Process Efficiency

Self-draining capability – designed for optimal air bubble escape and minimal residue
No field calibration required – integrated Heartbeat Technology enables automated verification
Seamless digital integration – supports modern single-pair Ethernet-based communication protocols